James Drife MD FRCOG FRCPEd FRCSEd Hon FCOGSA

  • Professor, Department of Obstetrics and Gynaecology, General
  • Infirmary, Leeds

It is particularly important to get this terminology right when treating young children for stuttering allergy testing nashville order 10 mg alavert amex. The first documented evidence of this idea appears to have been during the early 20 Century 13 at the University of Iowa allergy shots exhaustion order alavert toronto. So allergy shots chronic sinusitis order alavert cheap online, in a clinical sense allergy shots didn't work discount alavert 10mg without a prescription, it is appropriate to think of stuttering as momentary speech disturbances surrounded by otherwise normal sounding speech. In reality, though, it is possible that the speech physiology of those who stutter is unusual whenever they speak, but the only perceptible problems are what observers label as stuttering moments. Stutters, stutterings, dysfluencies, disfluencies the idea of stuttering moments has been popular since its inception, and to this day clinicians use it during clinical practice. In formal reports they may write moment of stuttering, stuttering moments, or stutterings, but those terms are generally thought to be too formal for speaking with clients and parents. It is more common for clinicians to refer to stutters or a stutter during clinical practice. Stuck words, bumpy words When talking to young children about their stuttering, clinicians need a different kind of language. Popular terms with young children are bumpy word or bumpy words, and sometimes, stuck word or stuck words are used. The important thing to remember here is the need to communicate effectively with the child about stuttering, so any terms that do that are useful. That ideal definition would contain words to make it clear who does and who does not have the disorder. Unfortunately, though, after a vigorous debate for a decade beginning during the early 1980s, the search for such a workable and generally agreed stuttering definition ground to a halt 21,22,23,24,25,26,27,28,29,30,31,32,33 without resolution. An important point here is that none of 30 the three definitions can be considered completely satisfactory. They all have limitations but also some strengths that make them useful in some professional contexts. The World Health Organisation definition 30 the most common definitions of stuttering are known as dictionary definitions. The World Health Organisation classifies 34 stuttering as a disability, and in 1977 offered what seems to be the most popular definition to date: Disorders in the rhythm of speech, in which the individual knows precisely what he wishes to say, but at the time is unable to say it because of an involuntary, repetitive prolongation or cessation of a sound. These disruptions (c) usually occur frequently or are marked in character and (d) are not readily controllable. Sometimes the disruptions are (e) accompanied by accessory activities involving the speech apparatus, related or unrelated body structures, or stereotyped speech utterances. Also, there are not infrequently (f) indications or report of the presence of an emotional state, ranging from a general condition of "excitement" or "tension" to more specific emotions of a negative nature such as fear, embarrassment, irritation, or the like. That is because there are no observable speech events that can be recorded with words 37 and which categorically distinguish between stuttering and normal speech. At some time everyone has normal disfluencies that can be described with the same terms that can be used to describe stuttering moments. That definition has 38 been criticised also because it contains "qualifiers and imprecise terms" (p. Another problem with dictionary definitions is that they overlook a well-known group who are never or rarely heard to stutter but who are troubled by the disorder nonetheless. For such people, speech behaviours cannot be used to define their disorder because they rarely, or sometimes never, show any observable stuttering moments. A strength of dictionary definitions Dictionary definitions of stuttering are useful ways to describe the disorder. For example, clinicians could use it, or variations of it, when describing the disorder to other health professionals or to the media. This contrasts it with the intended objective, observable features of dictionary definitions. Limitations of internal definition It has been argued that internal definition is more a statement about the nature of the disorder than a 41 definition. Also, this definition has in common with dictionary definitions that it fails to distinguish between stuttering and usual speech. Probably, all speakers would report that, at some time, they lose control of their speech. Of itself, that is not a particularly serious problem, but overall it is better if clinicians can observe the presence of the disorder. A strength of internal definition the internal definition of stuttering certainly is a valid one, because stuttering is fundamentally a private experience for those affected. The proponents of this definition even conducted an experiment 42 purporting to verify this. They showed that a speaker could distinguish recordings of real and faked stuttering shortly after producing them, but neither the speaker nor listeners could distinguish them at later times. Clinicians rely on internal definition of stuttering during routine clinical measurement of stuttering severity. As discussed during Lecture Four, it is essential to obtain client reports of how severe their stuttering is. When clients give you that information, they are, in effect, drawing on an internal definition of stuttering. If a client says that stuttering is not present, and has not been present for a significant period, that is important clinical information because of its validity. Another reason why internal definition of stuttering is valid is that it reflects what clinicians want to achieve for clients with treatment: a change of the experience of the disorder, and a positive shift of how they feel it affects them. In other words, a clinician who has consensus with a community of experienced speech-language pathology observers determines whether stuttering is present or whether it is not. The answer to that is conceptually simple; senior clinicians can mentor junior clinicians about what are appropriate judgements. And there is a risk that different clinical communities, such as those in different countries, may develop different perceptions about what stuttering is and what it is 43 not. Strengths of perceptual definition An advantage of perceptual definition is that it is procedurally simple and clinically workable if the required consensus exists. When parents bring children who have just begun to stutter to the clinic they are reporting their perception that stuttering is present. As discussed shortly, there is reason to believe that clinicians generally agree with parents in such cases. Describing stuttering moments 44 Johnson developed the first system for classification of stuttering moments. That taxonomy was developed specifically for stuttering during early childhood, and included eight terms: word repetition, sound/syllable repetition, phrase repetition, incomplete phrase, interjection, revision, broken word, 45,46 and prolongation. All those taxonomies deal with stuttering during early childhood, with the exception of one.

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The focus is on performance in the testing setting allergy medicine not working buy discount alavert, as well as on a task analysis of the cognitive requirements of home and work allergy report nyc order alavert online pills. Neuropsychological testing profiles can aid in identifying general categories of neurologic disease and conditions allergy medicine brand names order alavert 10mg on line. It is in this latter allergy symptoms cough dry buy alavert without a prescription, more descriptive role that neuropsychologists have made their most recent advances. Critical Thinking Questions Why are the concepts of reliability and validity so important in psychological and neuropsychological assessmentfi What kinds of questions and tests do neuropsychologists use in a neuropsychological evaluationfi What sort of recommendations and treatments can neuropsychologists give to brain-impaired people that will be useful in their daily livesfi How do the major two approaches (process and battery) to interpreting neuropsychological data differfi Key Terms Neuropsychological evaluation Base rate Orientation Normative data Psychometrics Achievement tests Sensation Cutoff score Standardized test Behavioral-adaptive scales Perception Specificity Reliability Intelligence tests Motor apraxia Sensitivity Validity Neuropsychological tests Ideomotor apraxia Normal distribution Construct validity Personality tests Malingering Deficit measurement Content validity Vocational inventories Interpretive hypotheses Pattern analysis Criterion validity Crystallized functions Standard battery approach Pathognomonic signs False positive Fluid functions Process approach Web Connections ericae. Within this site you can find concrete examples of simple statistical terms and validity and reliability procedures on interpretation discussed in this chapter. Evolutionarily old, one-celled creatures such as the amoeba show elementary responses to sensation and have decision-making capabilities. In their universe of a droplet of water, amoebas can move about, locate food, and engulf it. This unicellular organism uses complex electrochemical processes, but has no nervous system and no brain. Moving up the evolutionary ladder, increased complexity of behavior corre- sponds with a more specialized nervous system, which is essential for speeded communication. Of the two main types of cells, neurons alone account for about 100 billion cells, and estimates suggest that glial cells out- number neurons by 10 to 1. Considering there are approximately 6 billion people on earth, the number of cells in one human brain is more like the number of stars in the sky. If 1 neuron connected only to 100 others, the emerging network would be staggering in its size and complexity. However, evidence sug- gests that the number of connections actually ranges from 1000 to 100,000, averaging about 10,000 per neuron (Beatty, 1995; Hubel, 1988). Their processing systems require a great deal of energy and consume the most oxygen and glucose of any bodily system. This chapter focuses on the essential building blocks of thought and behavior: neurons and glial cells. Neurons and glia are classes of cells that contain subtypes based on their structure and function. Neurons are considered the most important cells, and the basic electrical-chemical processes of neuronal communi- cation have been well described by scientists. Although glial cells traditionally have been described as hav- ing a supporting function for neurons, science now suggests that glial cells may have a larger role to play in thought and learning. The neuron can be studied as a universe unto itself, but neuropsychology is also focused on the effect of behavior related to neuronal disruption. The ability of the neuron to repair itself is intriguing because of the enormous implications for treatment. The nervous system thus consists of separate units rather than the neuron differs from other cells in that it is spe- one continuous structure. To some degree all the neuron has often been studied by scientists with functions that sustain life, as well as those that make us the idea that by studying the fundamental parts, a better human, are coordinated and depend on the communica- understanding of the whole can be achieved. Reductionists may describe their work as mapping tion for brain science is to what extent neurons can re- the brain. The neuron hypothesis is in regenerate; for example, if surgeons reattach an ampu- accord with this viewpoint suggesting that (1) all neural tated finger, the finger may regain some mobility. Neu- function is refiected in behavior, and (2) all behavior has rons in the spinal cord and brain do not heal sponta- an underlying neural correlate (Pincus & Tucker, 1985). This is most evident in the complete severing of Reductionists argue that the healthy mature brain pro- neurons in the spinal cord, which leads to paralysis. In other words, the reductionist viewpoint ar- ongoing, so perhaps some day scientists will be able to re- gues that every human experience can be reduced to a verse spinal cord damage (Naugle, Cullum, & Bigler, 1998). Although reductionism is consid- Later in this section (see Regeneration of Neurons) we ered outdated and oversimplified because it is not possi- examine the question of neurogenesis, regeneration, and ble to correlate behavior with individual neurons, some attempts to regain function after injury. Terminal synaptic buttons treelike or feathery extensions that branch from the Neurons are specialized to exchange information, specifi- neuron into the immediate neighborhood of the cell cally the reception, conduction, and transmission of elec- body. They possess specialized structures, particularly termi- Cell Body nal buttons, which produce neurochemicals. Neurons communicate through an electrochemical integrity of the cell body that controls and maintains the process. Because these cell bodies are gray, the structure of neurons allows them to communicate the term gray matter is used to describe areas of the brain with each other in an interesting way. Neurons, however, commu- tein synthesis cannot occur in the axon, so all axonal pro- nicate with each other by axonal firing, which allows elec- teins come from the cell body. The process of such communica- Dendrites tion releases chemical neurotransmitters, permitting Neurons generally receive chemical transmissions from one highly sophisticated combinations of reactions that infiu- another through dendrites, feathery extensions that branch ence downstream neuronal behavior. There are often thousands of dendrites per neu- ation that differ from those of other body cells. In general, ron, and they differ in relation to the different functions of no new neurons form after birth (Cowan, 1990). The profuse branching of dendrites allows during certain periods of development, massive pruning them to receive communication from a large number of ax- occurs as important neural connections form in response onal terminals across the synapse. Axon Many dendrites are covered with spines, or small knobs, the axon extends away from the cell body. Its primary func- that form the synaptic connection with communicating tion is to transmit electrochemical information from the cell neurons. Dendrites are tiny, only visible under an electron body to the synapse through microtubules along its length. Neuroscientists estimate that the total possible long axons, some of them reaching from the lower end of connectivity among neurons in the human brain is approx- the spinal cord to the foot muscles. The layers of the myelin wrap around the axon increases the speed of axonal transmission (Beatty, 1995). Myelin is nodes of Ranvier interrupt it at regular intervals (see Fig- lipoprotein that wraps around the axon like the layers of ure 4. The projections of the surface membrane of each an onion, giving neurons their characteristic white mat- of those cells fan out and coil around the axon of neurons ter appearance. Because the nerve impulse jumps the axon, where the nerve impulse or action potential from node to node, the length of the myelin segment is of begins. The myelin sheath is formed can have a conduction velocity of up to 100 m/sec, may have myelin segments longer than 1 mm. Babies are unable to control their bladder and bowel functions: this is caused by insuffi- cient myelination of neurons; therefore, children cannot be toilet trained before about age 2 or 3. The speed of neuronal conduction is important in the adaptation of all species to potentially dangerous events in the environment. Zillmer the destruction of the myelin sheath perhaps one related to a demyelinating blindness), in the brainstem and cerebellum around the axon can result in significant slow virus or an autoimmune process (wide-based gait, intention tremors), and in and often striking behavioral changes, (Ebers & Sadovnick, 1993). Relapses are conditions are called demyelinating disor- remains an enigma, the course of the dis- usually acute and persist for several weeks. Death can result if the demyeli- implicated in the cause of the disease, most manifest visually (sudden unilateral nation affects vital centers of the brain.

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This may involve the combined use of airborne and contact precautions allergy symptoms list purchase alavert cheap online, in addition to standard precautions allergy forecast ann arbor purchase alavert 10 mg otc, until a diagnosis is established allergy forecast york pa cheap alavert 10mg without a prescription. Contain linen in a manner that prevents the linen bag from opening or bursting during transport and while in the soiled linen holding area allergy symptoms headache fatigue alavert 10 mg amex. The following information is from Interim Guidance on Planning for the Use of Surgical 92 Masks and Respirators in Health Care Settings during an Influenza Pandemic: Use of Surgical Masks and Respirators in Health Care Settings Surgical mask and respirator use is one component of a system of infection control practices to prevent the spread of infection between infected and non-infected persons. Staff with responsibility for direct patient care should be medically cleared, trained, and fit-tested for respirator use. If a vehicle without separate compartments and ventilation must be used, open the outside air vents in the driver area and turn on the rear exhaust ventilation fans to the highest setting. Required by State or Federal regulation, or representing an established association standard. Use barrier protective coverings as appropriate for noncritical equipment surfaces that are 136 1) touched frequently with gloved hands during the delivery of patient care; 2) likely to become contaminated with blood or body substances; or 3) difficult to clean. Avoid large-surface cleaning methods that produce mists or aerosols or disperse dust in patient-care areas. Promptly clean and decontaminate spills of blood or other potentially infectious materials. Follow proper procedures for site decontamination of spills of blood or blood- containing body fluids. Use standard cleaning and disinfection protocols to control environmental contamination during a pandemic influenza. When contact precautions are indicated for patient care, use disposable patient-care items. Follow these same surface cleaning and disinfecting measures for managing the environment of influenza patients. Use disposable, impervious covers to minimize body substance contamination to stretchers and surfaces when transferring or transporting bodies to morgue facilities. Those who physically handle remains may be at risk of blood borne or body fluid exposure requiring universal precautions and proper training for handling the dead. National Strategy for Pandemic Influenza Implementation Plan for the National Strategy for Pandemic Influenza. Also provides business planners with sector-specific and common pandemic information planning variables keyed to escalating disaster phases. Preparing for a Pandemic Influenza: A Primer for Governors and Senior State Officials Modeling Community Containment for Pandemic Influenza: A Letter Report Committee on Modeling Community Containment for Pandemic Influenza. This course is designed to be of use to all physicians who provide online medical direction to prehospital providers. Within the private sector, essential functions can be regarded as those core functions, services, and capabilities required for sustaining business operations. Since an influenza pandemic may affect regions of the United States differently in terms of timing, severity, and duration, businesses with geographically dispersed assets and personnel should consider dispersing their order of succession. Each organization must develop, update, exercise, and be able to implement comprehensive plans to protect its workforce. FluWorkLoss estimates the potential number of days lost from work due to an influenza pandemic. Because local outbreaks will occur at different times, have variable durations, and may vary in their severity, devolution planning may need to consider rotating operations between regional/field offices as a pandemic wave moves throughout the United States. The objective during recovery and reconstitution after a pandemic is to expedite the return of normal services and operations as quickly as possible. Replenishment of critical inventories is thus dependent upon an intact supply chain from manufacturing and distribution to transportation and receiving. However, financing from the Federal Government must be supplemented by funds from other public as well as private organizations. In addition, formal mutual aid agreements or other contracts should be developed in advance to document relationships, expectations and requirements related to obtaining emergency reimbursements. On the patient side, issues of financial access, such as requiring proof of insurance, apply. It is not likely that providers will be able to maintain documentation practices beyond what is considered minimally adequate to support treatment; altered standards of documentation for reimbursement purposes may have to be defined. Ensuring access to , and timely payment for, covered services during a pandemic will be 97 Robert T. It may also be necessary to extend certain waivers or develop incident-specific initiatives or coverage to facilitate access to care. Involving organizations and services designed to serve groups with special needs under normal conditions may be a successful approach. Populations recognized as having special needs in a mass casualty event include but may not be limited to the following: Children. The unique physiology and wide variation in physical and cognitive development by age within childhood requires that triage personnel be trained in pediatric triage standards and other pediatric assessment protocols; family care and adult care be available; appropriately-sized supplies, equipment, and medication doses be available; and safe use of decontamination procedures be ensured. Provisions should be made for screening and direction to appropriate services as part of triage or other assessment protocols. Individuals in these groups who are victims may require adjustments in treatment regimens and special monitoring, but these adjustments will be made within the context of any overriding goal to maximize lives saved. Although printed materials of a general nature may be prepared in advance, printed materials and signs will not be an adequate response for those who cannot read any language. The plan may have to provide for hold harmless agreements or grant immunity from civil or criminal liability under certain conditions. Minimally accepted levels of documentation of care provided to an individual may have to be established, both for purposes of patient care quality and as the basis for reimbursement from third-party payers. The plan may have to address the establishment and enforcement of isolation, quarantine and mass immunization and provisions for release or exception. The following recommendations are designed to protect healthcare workers, including emergency medical services personnel, during pre-hospital care and transport. Professor of Talmud, Yeshiva University, Professor of Jewish Law and Ethics, Benjamin Cardozo School of Law Rock Brynner, Ph. Professor of Clinical Emergency Medicine, Albert Einstein College of Medicine Carolyn Corcoran, J. Professor of Clinical Pediatrics, College of Physicians and Surgeons, Columbia University Joseph J. Chief, Division of Medical Ethics, Weill Medical College of Cornell University Rev. Director of Maternal Fetal Medicine, Lincoln Medical and Mental Health Center Hassan Khouli, M. Director, Pastoral Care, North Brooklyn Health Network, New York City Health and Hospitals Corporation John D. Deputy Director, Principal Policy Analyst Project Chair of the Ventilator Allocation Guidelines Valerie Gutmann Koch, J.

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However allergy vaccine order 10mg alavert free shipping, differing metabolites and toxins allergy forecast odessa tx buy alavert online now, capsules that pre- treatment philosophies allergy shots while taking beta blockers alavert 10mg with visa, increases in antibi- vent phagocytosis and facilitate abscess for- otic resistance over time allergy treatment bioallers buy generic alavert from india, and development mation, tolerance to air, and synergism with and increased use of more broad-spectrum other bacteria. Anaerobic bacteria most com- antibiotics have made it diffcult to gain con- monly produce 1) superoxide dismutase, sensus on a standard antibiotic treatment which aids in bacterial aerotolerance, 2) course. One of the frst (43) patients treated with penicillin, a policeman named Albert Alexander, suffered from a fa- Bacterial composition may infuence cial infection that developed as the result of a clinical presentation. Although Alexan- have sought to explain whether certain bac- der ultimately died of his infection, his case teria predispose a patient towards abscess is cited as an early success for antibiotic formation versus cellulitis. Results indicate treatment, since initially his clinical condition that cultures with isolates of peptostrepto- signifcantly improved once penicillin thera- cocci are more likely to manifest as a celluli- py was initiated, but after the limited supply this rather than an abscess. Numerous studies have demon- cillin in treating more advanced maxillofacial strated that transient bacteremia occurs after infections has declined. The potential for development of peni- to beta-lactams, clindamycin is the drug of cillin resistance during the treatment of a choice. Some evidence suggests course of antibiotics is generally considered that patients treated with penicillin or another adequate for the otherwise healthy outpa- beta lactam during the course of an infection tient. The Penicillin failure is more likely with more chances that penicillin-resistant bacteria signifcant and advanced infections. The patient is as- signed a total score which sums the values of Another study examining susceptibility each individual space involved. A signifcant controversy concerns the prophylactic use of antibiotics for certain In a comprehensive review, Flynn rec- procedures in patient populations that pres- ommended that amoxicillin be used as frst- ent an increased risk of developing a post- line treatment in the non-allergic patient with operative maxillofacial or systemic infection. Surgeons recommend prophylactic antibiot- postoperative pain, fever, and need for anal- ics in specifc circumstances for certain car- gesic medications. The oral and max- again, inadequate data exists to establish illofacial surgeon must be aware of the pos- clear guidelines. Even more controversial is the routine use of prophylactic antibiotics for infection Descending Necrotizing Mediastinitis prevention in otherwise completely healthy patients. Most authors consider this practice Descending necrotizing mediastinitis unsupported by evidence. The root tips with immuno-compromised patients such as of an infected maxillary tooth can cause si- those with diabetes mellitus or who are taking nusitis that tracks through the inferior orbital high-dose steroids. An infected maxillary ing fasciitis can occur in any type of patient, molar can travel posterolaterally into either and one case report has even described the the pterygopalatine or infratemporal fossae. The longer a necrotic tooth is pres- gical management, and can result in severe ent, the greater the likelihood of developing illness or death. These infections are mostly signifcant complications and the higher the likely to develop in the severely immunocom- risk of mortality. Rupture of the abscess can oc- cur spontaneously, presenting a risk for aspi- Two important fundamental questions ration. Additionally, airway compromise is a have been raised in the past regarding man- more signifcant concern in these areas, so agement of the patient who presents emer- the surgeon should always be prepared for gently with an odontogenic infection: 1) if the urgent surgical airway intervention. Finally, patient has cellulitis without clear evidence of erosion of the abscess into major vessels or an abscess, should an incision and drainage direct extension into the mediastinum is pos- be performedfi Palpa- Historically, timing of tooth extraction ble abscesses have been evacuated percu- has also been a source of controversy. Pa- taneously using the modifed Seldinger tech- tients presenting with odontogenic infections nique. In such an instance, the place- used, including Penrose, closed-suction, and ment of a peripherally inserted central cath- irrigating varieties. Patients with severe odon- surgical procedures occur in a non-sterile togenic infections often require the expertise environment (the mouth), different consid- of an experienced anesthesiologist, and f- erations must be evaluated by the treating beroptic intubation is the most commonly surgeon. In fact, in such a case, a 7-day should have her dental disease addressed course of antibiotics should be administered beforehand to avoid complications of preg- before performing debridement of the extrac- nancy. Although most antibiotics common- with identifying the source and extent of the ly used in the management of the maxillo- infection, the surgeon must also be aware of facial infection are safe, including penicillins the other host factors, including age, medical and cephalosporins, others, such as tetracy- history, and concurrent pregnancy, that may clines and metronidazole, should be avoided help predict the potential severity of the in- given their deleterious effects on the devel- fection and guide proper perioperative treat- oping fetus. Despite the constant evolu- ment and proliferation that normally occurs tion of bacterial defenses and ongoing devel- during pregnancy, bleeding is more likely opment of new antibiotics, this review should during intubation. Awake fberoptic intubation serve as a reminder that many of the classes is especially favored in this population, given of drugs traditionally used to treat oral and the higher propensity for airway obstruction. He completed his Oral the Division of Oral and Maxillofacial Sur- & Maxillofacial Surgry training from Parkland gery. Read-Fuller is serving as Immediate Past tory of involvement in clinical and laboratory President of the Resident Organization of the based anatomical issues and studies. He trained at Parkland Memorial Hopsital/University of Texas Southwestern Medical Center in Dal- las in the Division of Oral and Maxillofacial Surgery. Huang T, Liu T, Chen P, et al: Deep cervico-facial infection in Scotland neck infection: analysis of 185 cas- 2010: patterns of presentation, pa- es. Junaid A, Shah A and Elgazzar R: A is evidence-based dentistry, and do broad spectrum retrospective study oral infections increase systemic of odontogenic infection pattern and morbidity or mortalityfi Oral Maxil- management at a Canadian tertiary lofac Surg Clin North Am 23:491, care hospital. Burnham R, Bhandari R and Bridle dren hospitalized with maxillofacial C: Changes in admission rates for infections: a linear logistic model. Oral Surg cal odontogenic infection complica- Oral Med Oral Pathol Oral Radiol tions requiring hospital care. Zheng L, Yang C, Zhang W, et al: E, Verini-Aytes L, et al: Delayed-on- Is there association between se- set infections after lower third molar vere multi-space infections of the extraction: a case-control study. Zheng L, Yang C, Kim E, et al: the computed tomography and surgical clinical features of severe multi- fndings in maxillofacial infections. Rajasuo A, Nyfors S, Jousimies- role of bioflms in severe head and Somer H, et al: Bacteremia after neck infectionsfi Tomas I, Alvarez M, Limeres J, et al: fi-lactam antibiotics and increase Prevalence, duration and aetiology in the emergence of fi-lactamase- of bacteraemia following dental ex- producing bacteria in patients with tractions. Oral Maxillofac Surg tients which required third molar sur- Clin North Am 23:519, 2011. Vig N, Bhupal S, Shah S, et al: Is erative infammatory complications there any clinical beneft in routine- in the lower third molar surgery. Sandner A, Borgermann J, Kosling S, tiveness of antibiotic prophylaxis in et al: Descending necrotizing medi- third molar surgery: a meta-analysis astinitis: early detection and radical of randomized controlled clinical tri- surgery are crucial. Monaco G, Tavernese L, Agostini R, N, et al: Craniocervical necrotizing et al: Evaluation of antibiotic prophy- fasciitis: radiologic fndings in com- laxis in reducing postoperative in- parison to deep neck abscess. Leitner C, Hoffmann J, Zerfowski M, value of the laboratory risk indicator et al: Mucormycosis: necrotizing soft for necrotizing fasciitis score as an tissue lesion of the face. Sakkas N, Schoen R and Schmel- 20-year-old patient in right temporal zeisen R: Orbital abscess after ex- area. Teo N and Garrahy A: Elective sur- Br J Oral Maxillofac Surg 51:e199, gical cricothyroidotomy in oral and 2012. Elsharkawy R, Elmonoufy H, Za- ghloul M, et al: Oral infection as a risk factor for preeclampsia. Errors and omissions excepted, the names of proprietary products are distinguished by initial capital letters. All reasonable precautions have been taken by the World Health Organization to verify the information contained in this publication. However, the published material is being distributed without warranty of any kind, either expressed or implied. Increasingly, governments around the world are beginning to pay attention to a problem so serious that it threatens the achievements of modern medicine. Non- or emergence in other regions, of artemisinin- representativeness of surveillance data is a limitation resistant strains could jeopardize important recent for the interpretation and comparison of results. The chosen bacteria underrepresented among samples, leading to gaps are causing some of the most common infections in in coverage of important patient groups.

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