Lee A Fleisher, MD, FACC

  • Robert Dunning Dripps Professor and Chair of Anesthesiology and Critical Care Medicine, Professor of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania

https://www.med.upenn.edu/apps/faculty/index.php/g319/p3006612

Changes in visual felds Assess visual feld changes and manage as recommended in the Optometric Clinical Practice Guideline on Care of the Patient with Visual Impairment allergy medicine for 7 year old generic 20mg prednisone with amex. Eye Cranial nerve palsies Assess multiple diagnostic positions of gaze; tests of smooth movement pursuits (versions and ductions) allergy generator order prednisone with a visa, and saccades allergy shots unitedhealthcare order 5mg prednisone with mastercard. Pupils Sluggish pupillary refexes Rule out optic neuropathy and other neurological etiologies allergy testing san diego purchase prednisone 10 mg with visa. Cornea Reduced corneal sensitivity Monitor for abrasions, keratitis, or ulcerations. Monitor contact lens wear as recommended in the Optometric Clinical Practice Guideline on Care of the Patient with Contact Lenses. Recurrent corneal erosions Prescribe sodium chloride solution/ointment or ocular surface lubricant. Iris Rubeosis iridis Gonioscopy to rule out anterior chamber angle involvement (neovascularization on the iris) and neovascular glaucoma. If functional defcits remain, manage as recommended in the Optometric Clinical Practice Guideline on Care of the Patient with Visual Impairment. Surgery may be indicated, if adequate visualization of the retina is no longer possible or if visual acuity is decreased secondary to the cataract. Refer to Optometric Clinical Practice Guideline on Care of the Adult Patient with Cataract for more information. Detachment Consultation with an ophthalmologist experienced in the management of diabetic retinal disease. Optic Disc Papillopathy Management of diabetic papillopathy or ischemic optic neuropathy may require consultation with a neuro Ischemic optic neuropathy ophthalmologist or neurologist to rule out all other potential etiologies. Since the relative diseases due to the high rate of patients that may risk of vision loss in patients without high-risk subsequently need laser or surgical intervention. The follow proliferation of fbrous tissue on the optic disc or up interval may be extended based on disease elsewhere on the retina. Frequent consultation with an ophthalmologist experienced follow-up is needed to determine whether in the management of diabetic retinal disease. Such patients should be re loss, increased the chance of visual improvement, examined within 4 to 6 months. Follow-up for decreased the frequency of persistent macular proper management of the retinopathy can be 28,29,31,33 edema, and caused only minor visual feld losses. An average [Evidence Strength: A, Recommendation: A) of 8 to 9 intravitreal injections may be needed in the frst year of treatment. Furthermore, focal/grid laser at the known to be associated with an increased initiation of intravitreal ranibizumab is no better, risk of stroke. It is unknown if a substantially and is possibly worse than, deferring laser for at smaller dose, when used intravitreally, has 177 least 24 weeks in these eyes. The trials employing the same standardized procedure risk of such events with systemic administration for the preparation and intravitreal injection using was found to be 5 percent. Telehealth Programsthe vast majority of persons with diabetes will develop diabetic retinopathy at some point during Ocular telehealth programs can be an integral the course of the disease. Studies across multiple aware that retinopathy may exist even when vision is populations demonstrate that the prevalence of good and in the absence of any symptoms. Optometrists should help patients understand that timely follow-up examinations and management arethe implementation of national coverage of universal critical for early diagnosis and intervention, when retinal evaluation for all patients with diabetes indicated, to reduce the risk of vision loss from mellitus has been shown to reduce the incidence diabetic retinopathy. Individuals should also be of blindness among patients with diabetes by as informed about their higher risk for other non-retinal 192,193 much as 95 percent. Telehealth programs have ocular complications, such as cataracts, neovascular been largely used in these initiatives and rely on glaucoma and open angle glaucoma, and informed the digital capture and transmission of standardized about available optometric vision rehabilitation care ocular images and patient health information for to address loss of visual function. Proper monitoring interpretation and evaluation by trained observers and timely treatment can result in subsequent saving who can generate a treatment and care plan. Telehealth has the potential to Individuals should also be encouraged to participate deliver economical, high quality eye care locally, in diabetes education programs. Substantial opportunity exists to detection and assessment of the severity of diabetic further improve diabetes control and, thus, to reduce 188 195 retinal disease when implemented appropriately. In addition, there is a clear need to increase the Specifc emphasis should be placed on the beneft frequency of smoking cessation counseling for of reduction in elevated A1C in lowering the risk of patients with diabetes, given the strong association damage. For the individual with proliferative retinopathy, the risks of smoking related to diabetes and the same one percent increase in A1C results in 145 encouraged to quit smoking and/or seek smoking 60,92,203 percent progression over 10 years. Prognosis and Follow-Up Persons should be informed of the relationship between the level of glycemic control and the risk of Disability and premature death are not inevitable 43 9 consequences of diabetes. Lifestyle and behavioral Appropriate communication with the patients primary modifcation, and pharmacotherapy, can delay care physician (as with any referral consultant) is progression to type 2 diabetes among persons critical for proper coordination of the patients care. All health care personnel involved with the individuals care should be aware All persons with diabetes mellitus are at risk for of his or her overall medical status. These Adherence to treatment recommendations to letters also provide permanent documentation for the maintain optimal control of blood glucose levels is patients record. These fndings mellitus includes individualized glucose targets may be due to improvements in the management and lifestyle modifcations. The individuals age, of risk factors (hyperglycemia, hypertension and weight, comorbidities, race/ethnicity, and physiologic hyperlipidema) and overall diabetes care, along with differences need to be considered in determining 115 78,208 earlier identifcation of diabetes. Others, who have only limited presence and severity of retinopathy at the time of residual insulin secretion, often require insulin for 207 the patients initial eye examination. Individuals with type 1 diabetes, who have extensive beta-cell destructionthe follow-up examination of persons with diabetic and therefore no residual insulin secretion, require retinopathy should be scheduled in accordance with 6 insulin for survival. While previous standards for diabetes management emphasized the need to maintain glucose levels Laser photocoagulation greatly improves the as near to normal as safely possible, current prognosis for maintaining useful vision. According to (panretinal) laser photocoagulation reduces the risk of the American Diabetes Association, reducing A1C severe vision loss (best visual acuity < 5/200) to less levels to less than 7 percent has been shown to than 2 percent per patient. For individuals with the relative risk of severe hypoglycemia by 30 214 a history of severe hypoglycemia, limited life percent. The classic symptoms of with diabetes should be individualized, taking hypoglycemia are hunger, shakiness, nervousness, 215 into consideration their risk of hypoglycemia, sweating, or weakness. While hypoglycemia is anticipated life expectancy, duration of disease more common in type 1 diabetes, the incidence is and co-morbid conditions. However, as persons experience more frequent low blood In persons with type 2 diabetes mellitus, intensive glucose, they gradually lose the classic symptoms glucose control may reduce microvascular disease, of hypoglycemia due to defective glucose counter 210 216 retinopathy, nephropathy, cataract and neuropathy, regulation (hypoglycemia unawareness). To help (B/B) non-fatal myocardial infarction and lower identify persons experiencing hypoglycemia, the extremity amputation. It may be prudent for optometrists offces to maintain a blood glucose meter and single use lancet Intensive glucose control in individuals with type 2 devices for confrming hypoglycemia and its resolution diabetes and established cardiovascular disease or where state laws permit. Check blood glucose to confrm hypoglycemia have no signifcant impact on the risk for nonfatal (blood glucose <70 mg/dL). If patient is conscious, give 15 g of simple as a strategy for reducing such events in individuals carbohydrates orally as immediate treatment. If initial blood glucose is While achieving tight glycemic control may reduce less than 50 mg/dL, give 30 g of simple 45 carbohydrates. If blood glucose is less than 70 mg/dL repeat However, the Wisconsin Epidemiologic Study of the treatment (step 2) until blood glucose returns Diabetic Retinopathy showed that elevated blood to at least 90 mg/dL. Inject glucagon intramuscularly, if it is available in the Individuals with type 2 diabetes mellitus have an offce. Slight Recommendation: B] variations in optimum blood pressure for people As a preventive approach, persons with with diabetes can be cited in the literature. Blood diabetes should be treated as if they have pressure of <140/80 mmHg has been recommended 78 cardiovascular disease. There is emerging evidence that normalizing blood lipid levels may also reduce the risk of retinopathy. Weight Management Intensive treatment of dyslipidemia using a Being overweight or obese is associated with combination of simvastatin and fenofbrate, along with increased risk of developing type 2 diabetes. It intensive glucose control, has been shown to slow is important for individuals to understand this the rate of progression of diabetic retinopathy in type 218 association, as well as how to prevent or remedy 2 diabetes mellitus. Among those who and its progression independent of its lipid modifying 221 have pre-diabetes or are at high risk for developing action. Cardiovascular risk reduction 7 percent combined with 150 minutes of physical activities per week signifcantly reduces the likelihood 89the major cause of death and complications of developing diabetes. Persons with type 2 Very obese adults, who are at high risk for diabetes have a substantially increased risk of developing diabetes, can reduce their cardiometabolic cardiovascular disease compared with persons risk with primary care weight management.

purchase prednisone cheap

Ermittung von Erholung-spausen fur before and after participation in a functional sports statische Arbeit des Menschen allergy shots at walgreens buy prednisone 5mg. A comparison of closed kinetic chain and knee during a resisted single-limb squat exercise allergy symptoms 3dp5dt generic prednisone 40 mg without prescription. Sensory nerve endings in the cat cruciate ligaments: Sumen Y allergy symptoms 8 months order on line prednisone, Ochi M allergy partners of richmond generic 10mg prednisone with amex, Adachi N, Urabe Y, Ikuta Y. Estrogen level alters the failure load of the rabbit exercises in healthy individuals. The menstrual cycle, sex activity in open and closed kinetic chain exercises hormones, and anterior cruciate ligament injury. Comparison of 2 eccentric exercise protocols influenced by activity in receptor afferents from the for patellar tendinopathy in volleyball players. Effect of ankle position on isometric quadriceps Influence from stretch-sensitive receptors in the strengthening. Sensorimotor control for knee pain and knee osteoarthritis: randomised of knee stability. The effects of Six-week high-intensity exercise program for middle human ankle muscle vibration on posture and balance aged patients with knee osteoarthritis: a randomized during adaptive locomotion. Electromyographic analysis of the medialis obliquus: vastus lateralis muscle integrated anterior cruciate ligament-deficient knee. Comparison of strength training program on gait velocity and balance effects of exercise programme, pulsed ultrasound and of older adults. Recent advances in with osteoarthritis of hip or knee: nine months follow the rehabilitation of isolated and combined anterior up. Effectsthe optimal training load for the development of of exercise adherence on physical function among dynamic athletic performance. Speed-strength preparation ofthe effect of an impulsive knee valgus moment on future champions. The effect of exercise Waddington G, Seward H, Wrigley T, Lacey N, regimens on reflex response time of the vasti muscles Adams R. Comparing wobble board and jump in patients with anterior knee pain: a prospective landing training effects on knee and ankle movement randomized intervention study. Effects of aquatic exercise on flexibility, in patellofemoral pain: a 5-year prospective randomized strength and aerobic fitness in adults with osteoarthritis study. Materials fatigue initiates eccentric contraction exercises for patellofemoral pain. Static and dynamic Witvrouw E, Lysens R, Bellemans J, Peers K, balance responses in persons with bilateral knee Vanderstraeten G. Comparison of closed and open kinetic on anterior cruciate ligament injuries in women as chain exercise in the anterior cruciate ligament determined by hormone levels. The effects of aquatic and traditional exercise programs on persons with knee osteoarthritis. Comparison of closed and open kinetic chain exercise in the anterior cruciate ligament-deficient knee. The effectiveness of eccentric quadriceps muscle training in decreasing tendon pain and improving lower extremity function in patients with chronic patellar tendinitis. Eccentric decline squat protocol offers superior results at 12 months compared with traditional eccentric protocol for patellar tendinopathy in volleyball players. Manual therapy involves passive stretching and Progression Concepts manipulation techniques aimed at restoring joint function for the Hip Joint. The current definition of manual therapy practice includes exercise as a component and is not limited Section 2: Stage 2 Exercise to passive joint treatments. Orthopaedic Manual Therapy is Progression Concepts a specialized area of physiotherapy/physical therapy for the for the Hip Joint. While both exercise and manual therapy have been shown to be effective on painful hips, Hoeksma et al. They found manual therapy to be more effective than exercise alone in the treatment of hip osteoarthritis. Exercise is a part of manual therapy and a combined approach of both passive and active treatment is recommended, as neither can be fully replaced by the other. Passive joint mobilization and soft tissue work may be necessary prior to initiating exercise. This Progression Concepts chapter will attempt to focus on exercise concepts and for the Sacroiliac Joint. The reader is also encouraged to review the Hip and Lumbar chapters for integration into a Section 2: Stage 2 Exercise more complete exercise program, should these areas require Progression Concepts treatment as well. A detailed evaluation of the related anatomical systems must be performed to identify load sensitivity of key ligamentous and fascial structures, as well as abnormal function at the articulations between the ilia and sacrum, and the pubis. Evaluation must also include assessment of the motor system, including volume, coordination and strength. Muscles of the hip, pelvis and lumbar spine must function in proper synergy to be transducers of force between the lower limb and the upper and lower torso. It is assumed the reader has an extensive knowledge of sacroiliac joints and pelvic girdle anatomy, with a basic understanding of biomechanics. This chapter will provide limited reviews of these sciences, with emphasis on exercise application. The ligamentous and capsular structures close to the instantaneous axis of motion, as well as collagen structures more distal to axis, need to be able to resist up to 4,800 N of force (Gunterberg et al. Unfortunately, Progression for the in reviewing the randomized trials, it is clear that the Lumbar Spine. This resulted in very heterogeneous populations of subjects Section 3: Stage 3 Exercise with low back pain being treated with specific exercise Progression for the approaches. After detailed tissue differentiation, exercise can be applied to not only improve symptoms and function, but to assist in facilitating tissue repair. Tissue differential diagnosis is challenging, yet it should remain a goal with each patient to better establish a treatment program. Even if an evaluation fails to identify a specific tissue, many tissues can be ruled out and any contraindications can be identified. Also, a pattern of symptoms with compression or tension can be established to assist in designing a safe program to improve tissue tolerance. Much of the literature addressing the application of exercise in the treatment of lumbar pain has identified two main properties: muscle strength or motor control.

Purchase prednisone cheap. Baby | Official Trailer Reaction [HD] | Netflix| DREAD DADS PODCAST | Rants Reviews Reactions.

To examine pre-metastatic niche formation allergy symptoms 7dpo purchase prednisone 40 mg, a mouse model utilizing tail vein injection of E0771 cells was used allergy symptoms vomiting diarrhea prednisone 5 mg otc. Results: We found that obesity significantly increased S1P levels in serum from breast cancer patients allergy symptoms but low pollen count order prednisone online pills. Despite modern diagnostic techniques such as high-resolution ultrasound allergy symptoms oregon buy on line prednisone, it remains a challenge to differentiate ovarian cancer from metastatic breast cancer with peritoneal manifestation before or during surgery. Specifically, we asked the question whether there are predictive factors in primary breast cancer associated with subsequent development of peritoneal metastasis. Patients and methods: We identified 58 patients with ovarian metastases in the Charite cancer register (4,792 breast cancer patients from 2003 to 2015). Median age of all patients with primary breast cancer was 60 years (10%-90%: 41-75). There was a significant difference in age at diagnosis of metastasis between patients with (50. Body: Cancer is often driven by deregulated protein kinases pathways including breast cancer. To profile the kinome at the protein level we are developing a kinase pulldown (KiP) proteomic platform that uses multiple kinase inhibitors conjugated to sepharose beads for protein kinase profiling. Mass spectrometry-base tryptic peptide sequencing is used to identify and quantify the kinome in an unbiased manner. In these analyses we have begun to explore the kinome interactome because we have observed that KiP also pulls down breast cancer subtype specific kinase interacting proteins that may represent new biological insights. Body: Metastasis is a lethal manifestation of cancer, the development of which is the major cause of death in cancer patients. There were no differences in proliferation in vitro or when implanted into the mammary gland of immunocompetent mice. In a parallel study where the established orthotopic primary tumor was resected, survival was significantly extended in mice bearing 4T1. Body: Background: Obesity increases the risk of many types of cancer, including breast cancer. The underlying mechanisms that drive obesity-related breast cancer remain unclear. Downregulation of this protein may be useful to prevent and/or treat these tumors. Body:the dual role of autophagy in breast cancer initiation, progression and responsiveness to various therapies is the focus of extensive studies. Our goal is to assess the relationship of expression of certain autophagy related genes in primary breast carcinomas to predict risk of recurrence. Our hypothesis includes the caveat that unique gene expression subsets will be deciphered by utilizing Laser Capture Microdissected breast carcinoma cells from tissue biopsies containing many cell types. Collectively, results suggest that expression of certain autophagy related genes may serve as biomarkers for assessing prognosis of breast carcinoma thus impacting clinical management of breast cancer. Body: Background: Metastasis and therapeutic resistance are major issues in treating patients with breast cancer. One type of secreted mucin, Mucin-2 (Muc2), is expressed in some breast cancers, but is absent in non-neoplastic breast tissue, suggesting that it plays a role in modulating breast cancer biology. Whether Muc2 expression correlates with breast cancer patient survival is controversial. This study examined the role of Muc2 in modulating breast cancer cell proliferation in vitro and in vivo, response to chemotherapy, and metastasis. Methods: Two novel cell lines were developed from patient derived tumor xenografts. Proliferation in vitro was measured using the IncuCyte live cell imaging system and crystal violet staining. Response to chemotherapy was measured by examining apoptosis using cleaved-caspase 3 expression. Conclusions: Muc2 expression plays an important role in mediating proliferation, apoptosis and metastasis of breast cancer cells. These data suggest that Muc2 is important in controlling the biology of Muc2 positive breast tumors. In addition, Muc2 may be important in guiding treatment and predicting outcomes in breast cancer patients. Body: Background: Invasion is a fundamental step in metastasis, the leading cause of breast cancer-related death. We have shown previously that primary breast tumors invade collectively as clusters of cancer cells (Cheung et al. These clusters are led by a small subpopulation of cancer cells that highly express the basal epithelial protein cytokeratin 14 (K14) and other stem cell genes (Cheung et al. K14+ leader cells metastasize as clusters, reverting to a proliferative growth state upon colonization of a secondary site (Cheung and Ewald. The mechanisms regulating their transitions between collective invasion and growth states remains poorly understood. Understanding these mechanisms could produce new insights into tumor cell collectivity and uncover new ways to treat disseminated cell clusters that have already metastasized. Body: Metastasis and endocrine resistance are two factors that complicate therapeutic intervention in breast cancer patients and lead to poorer overall survival. Body: Background Recently it was shown that tumor cell dissemination is an early event in breast cancer progression (Hosseini et al. Exclusion criteria were presence of invasive breast cancer, bilateral or metastatic disease as well as other malignancies in their history. The number of distant metastases in women without invasive local recurrence detected in this cohort was comparable to earlier findings at different centers. This study warrants further investigations concerning evolutionary relationship between primary tumor, minimal residual disease, local recurrence and clinically detectable macrometastases. Met250Thr) mutation in enhancing cellular invasiveness of breast cancer 1 1 1 1 1 1 1 1 1 Ning Liao, Guo-Chun Zhang, Yulei Wang, Li Cao, Kai Li, Chong-Yang Ren, Ling-Zhu Wen, Yumei Shi, Wenzhen Zhu and 1 1 Xiaoqing Chen. Cancer Center, Guangdong General Hospital & Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China. However, the functional roles for these novel mutations in the cellular biology of breast cancer remain to be elucidated. Body: An increasing number of studies have found that other cells in the tumor microenvironment can influence tumor cells. Adipocytes, which were once thought to function only in energy storage, are now considered an active endocrine organ that secretes pro-inflammatory cytokines and proteases. In human breast cancer patients, invading tumor cells are surrounded by mature adipocytes. The presence of the changed adipocytes then increases the invasion capacity of breast cancer cells. It causes changes to adipocytes and the surrounding microenvironment by invasion of macrophage cells. The effects of obesity-induced macrophage invasion have not been well characterized in the sector of breast cancer-adipocyte crosstalk. When macrophage conditioned media was added to adipocytes and breast cancer cells in co-culture, the breast cancer cells showed increased cell proliferation and migration abilities. Experimental co-culture (adipocytes, breast cancer cells, macrophage conditioned media) showed almost twice the number of cells than the control co-culture (adipocytes, breast cancer cells, non-conditioned media). Interestingly, breast cancer cells alone in macrophage conditioned media did not show an increase in proliferation. This shows that macrophages may not affect breast cancer proliferation directly, as all three cell types are needed for increased proliferation of breast cancer cells. Introducing macrophages into this crosstalk also resulted in increased migration abilities. After 24 hours, breast cancer cells grown in experimental co-culture migrated further to close a wound than breast cancer cells grown in control co-culture. These results show that macrophages can affect adipocyte-breast cancer cell crosstalk.

prednisone 40 mg fast delivery

These serious risks led to the need special treatment in the perioperative period allergy testing mckinney order generic prednisone. There recommendation that cataract surgery be delayed in patients are multiple treatment options for these patients at the time with diabetes allergy forecast kingston ontario cheap prednisone master card. By contrast allergy medicine everyday buy prednisone with american express, retinal nerve the highest oxygen consumption per gram of tissue of all cells are transparent and not visible by ophthalmic or the organs of the human body allergy testing edinburgh buy prednisone 40mg otc. Layers of retinal neurons and nutrient demand, the retinal neurons that provide vision are their synapses can be seen by optical coherence tomog heavily dependent on an adequate blood supply. B) Wide-feld fuorescein angiogram illustrating zones of retinal nonperfusion (*), difuse microvascular leakage consistent with common retinal fndings include microaneurysms, breakdown of the blood-retinal barrier, and prominent leakage temporally intra-retinal hemorrhages, hard exudates, edema or associated with pathologic neovascularization. Microaneurysms, intraretinal hemorrhages, hard exudates, cotton wool spots, and intraretinal microvascular abnormalities are visible. Although the retina can be visualized directly using First, retinal nonperfusion 6) leading to ischemia specifc lenses in combination with an appropriate light can directly impair retinal function. These friable vessels can bleed neovascularization and nonperfusion in the periphery that into the vitreous cavity causing vitreous hemorrhage, and are not otherwise apparent 6), and this fnding the fbrotic components can contract and cause retinal may alter classifcation and prognostication compared detachment 7). Factors such as diabetes duration, sex, and genetic susceptibility obviously cannot be altered. However, metabolic control, blood pressure, renal function, lipid levels, and nonhealing ulcers are modifable and should be addressed in a comprehensive manner coordinated with patients, their physicians, and ophthalmologists (82). However, this Most of these trials enrolled patients with 20/40 or worse defnition has become outdated. Specifcally, laser of visual acuity (since fve letters represent one line), or the photocoagulation signifcantly reduces the risk of moderate equivalent of an eye improving from 20/60 to 20/40 visual visual loss by approximately 50%, a protective effect that acuity. In comparison, patients treated with macular laser is independent of baseline visual acuity (85). Despite its therapy or observation gained little or no visual acuity over potential value in slowing the progressive visual loss from the same time period. Among better-seeing eyes, all three is defned by thickening that affects the 1-mm-diameter agents (bevacizumab, ranibizumab, and afibercept) central sub-feld of the macula. All are given by direct injection three medications achieved robust visual acuity gains, into the eye in an in-offce procedure called an intravitreal afibercept achieved the greatest visual and anatomic gains (or intravitreous) injection. Engineered proteins, including compared to bevacizumab, with similar ultimate visual the U. In these cases, incorpo lead to more complete loss of vision, with more profound ration of an intravitreal steroid agent can lead to better impairment in performance of activities of daily living. The two approaches are often Despite their potential extended durability compared used in combination. In comparison, the natural 43% still requiring four or more injections in the ffth year history of diseases that routinely affect both the macula of management (101). To better defne the risk-beneft ratio in increased risk of disease progression and visual loss. More recently, the feld has realized that position on improvement at 6 and 12 months compared to 6 and 15% this scale can be modifed with pharmaceutical treatment. Network Protocol S, just 66% of living patients are widely available and are often used even when patients completed the 5-year endpoint (101). If patients receive appropriate screening and approximately 25% were lost to follow-up for more than follow-up care, much of the visual impairment associated 12 months. Living with diabetes means managing and coping with Diabetes requires lifelong self-care and discipline, and the condition every hour of every day. This constant many people with diabetes self-manage the disease in the effort can be exhausting and stressful for patients and absence of any day-to-day positive feedback. Thus, it is emotional support and encouragement from health care not surprising that people living with diabetes have a providers and others is essential to strengthening patients higher risk of developing emotional problems than the motivation to perform routine self-care tasks and thereby general population (114). Distress and depression in people physical and mental well-being, particularly for people with diabetes can lead to worsening of metabolic control living with diabetes (112,113). This chapter provides and a higher rate of complications, which may in turn primary care providers with practical tips for empowering lead to end-organ damage and possibly death. Put simply, 16 diabetes-related distress and depression can limit a persons understanding manner; often, it is not what is said, but functional ability and coping mechanisms and thereby have rather how it is said that will be remembered. This anxiety is heightened by the fact that individuals living for many years with diabetes are 25 times more Sticks and Stones:the Language of Diabetes likely to experience visual impairment than those A familiar childhood saying teaches that sticks and stones without diabetes (116). Try to avoid language that implies a moral cations on the Internet may further exacerbate patients judgment about behaviors and blame. For accept that patients have the right to make choices, and use most of us, the world is what we see through our eyes. Having Patients express fears about losing their ability to work diabetes is frustrating, challenging, and distressing for many and thereby maintain their standard of living, ensure people. When we focus on what is perceived as patients their fnancial security, and support their family. They nonadherent behavior, we can dismiss the efforts patients also worry about the costs of care, rising insurance are making. Remember that wellness and health involve premiums, and higher copayments that could come with more than just gaining control or achieving a number on needed specialty care. For many people, the prospect patients using appropriate and encouraging language (118). Loss of vision may It can be argued that the role of physicians is evolving mean having to give up driving, reading, playing sports, toward patients being at the center of care and physicians or other activities. Physicians empower It has been well documented that the psychological their patients to use available resources, wanting what is well-being of patients plays a pivotal role in day-to-day best and practicing under the guiding principle to frst, self-management of diabetes (112,113). Language can empower people focus on what they stand to lose along with their vision. Words can link people Patients often express concern over the potential loss of together, spread knowledge, and improve self-image. Words can completely wipe out a part of As care providers, it is important for us to acknowledge someones identity and can leave a negative impression, our patients fears; it is also our responsibility to help our causing their emotions to defate. Language cannot be patients move beyond their fears and reclaim a positive separated from thought or experience. Empowering language should be used to educate and Patients fnd it reassuring to hear from their primary care motivate people with diabetes. When people use language recognize that visual impairment does not mean they will to shame and judge others, it can contribute to diabetes be unable to manage their diabetes. Patients with diabetes distress and ultimately slow progress and hinder diabetes and visual impairment can learn new skill sets that allow outcomes. Furthermore, people with diabetes may do them to live independently and remain productive. Sadly, it is concern about and fear of going blind that There are effective ways of communicating about diabetes. Avoid using a disease to describe a person, and diabetes-related visual loss can be avoided with appropriate avoid describing people as a disease. Suggested replacement treatment (122), less than two-thirds of patients in the language would include foot ulcer, infection of the United States are receiving appropriate screening (123). When in Eye Exams, Timing, and Experience doubt, remember that person-frst language puts the person As covered elsewhere in this compendium, eye examina frst (117), so call people with diabetes by their name. Using tions are recommended for patients with diabetes, as mindful language is a simple shift that can have a powerful these patients can remain asymptomatic even in advanced effect in reducing stigma and negativity. There are several components to an eye As health care professionals, we should work toward exam that is performed by an ophthalmologist (medical person-centered care that is based on respectful, inclusive, doctor) or optometrist, and patients should be told what to and empowering interactions (48). The typical eye examination begins with an initial to respect the language used when counseling our patients screening during which a technician may take a complete and should be selecting strength-based, collaborative, and medical history, including a complete list of the patients person-centered messages that encourage people to learn medications and allergies. Both near and distance vision is about and take action to manage complex diseases.