Devin O'Brien-Coon, M.D., M.S.E.
![]() https://www.hopkinsmedicine.org/profiles/results/directory/profile/10003798/devin-obriencoon For each of the following functions hiv infection overview buy 5 gm zovirax cream with amex, calculate the appropriate deriva tive antiviral tablets buy 5 gm zovirax cream amex, and show that the function satis? For what value(s) of these constants does this function satisfy the equation dy (a) dt =? Note: an equation which involves a function and its derivative is called a differential equation hiv symptoms eye infection order cheapest zovirax cream and zovirax cream. Note: all your answers should be exponential functions stages of hiv infection and treatment order generic zovirax cream from india, but they may have different dependent and independent variables. Find the appropriate differential equation that describes this growth, the appropriate initial condition, and the exponential function (with base e) that is the solution to that differential equation. In underdeveloped countries, people on average live to age 60 and women have a child roughly every 4 years between ages 13 and 45. Compare the per capita birth and mortality rates and the predicted pop ulation growth or decay in each of these scenarios, using arguments analogous to those of Section 11. Find the growth rate k in percent per year and the doubling time for the growing population. The population density, P(t) is found to satisfy the differential equation dP(t) = bP(t)? This means that, on average, each member of the population results in 5 newborn rodents every 100 days. Sup pose that over the period of 1000 days there are no deaths, and that the initial population of rodents is 250. A bacterial population grows at a rate propor tional to the population size at time t. By experiment it is determined that the population at t = 10 min is 15,000 and at t = 30 min it is 20,000. A colony of bacteria is treated with a mild antibiotic agent so that the bacteria start to die. It is observed that the density of bacteria as a function of time follows the approximate relationship b(t) = 85e? Determine the time it takes for half of the bacteria to disappear; this is called the half-life. Suppose the reaction mixture initially has concentration 1M (?1 molar?) and that after 1 hour there is half this amount. The concentration of the substance is observed to change at a rate proportional to the current concentration. This means that after 5730 years, a sample of Carbon 14, which is a ra dioactive isotope of carbon, has lost one half of its original radioactiv ity. For example, a sample 5730 years old has only one half the original activity level, i. If a 1 gm sample of material is found to have 45 decays per hour, approximately how old is it? Note: 14C is used in radiocarbon dating, a process by which the age of materials containing carbon can be estimated. Libby received the Nobel prize in chemistry in 1960 for developing this technique. If you begin with a sample of 800 units, how long does it take for the amount of radioactivity of the strontium sample to be reduced to (a) 400 units (b) 200 units (c) 1 unit 11. We encountered a differential equation that tracks changes in cell mass due to nutrient absorption and consumption. In applications studied, that function can be interpreted as predictions of the behaviour of the system or process over time. We then examine a simple class of differential equations that have many applications to processes of production and decay, and? Finally, we show how an approximation method provides for numerical solutions of such problems. Given a function, check whether that function does or does not satisfy a given differential equation. The expressions we get by evaluating each side of the differential water h(t) in the container satis? Create a table to organize the calculations for this example, To show that the differential equation (12. In others, some transformation that changes the problem to a more familiar one is helpful an example of this type is presented in Section 12. In many cases, particularly those of so-called non-linear differential equa tions, great expertise and familiarity with advanced mathematical methods are required to? Describe a variety of related examples, and use the same methods to solve and interpret these (examples include chemical production and decay, the velocity of a skydiver, the concentration of drug in the blood, and others). In this section we introduce an important class of differential equations that have many applications in physics, chemistry, biology, and other applica tions. Here we Then, since a,b are constants, we recognize that show two typical initial values of z, where z = y? We have arrived at the conclusion that the deviation from steady state decays exponentially with time, provided that b > 0. Hence, we already know that y should get closer to the constant value a/b as time goes by! We can do even better than this, by transforming the solution we found for z(t) into an expression for y(t). Rewrite these four initial conditions By solving the above problem, we get a detailed prediction of cell growth as the initial deviations away from steady state, that is, give the initial based on assumed rates of nutrient intake and consumption. Depending on whether the object is cooler or warmer than the environment, it heats up or cools down. From common experience we know that, after a long time, the temperature of the object equilibrates with its environment. Isaac Newton formulated a hypothesis to describe the rate of change of temperature of an object. He assumed that the rate of change of temperature T of an object is proportional to the difference between its temperature and the ambient temperature, E. Mastered Material Check Suppose the object is warmer than its environment (T(t) > E). But this does not agree with our everyday experience: a hot cup of coffee cools off in a chilly room. Typically, given the temperature at some initial time T(0) = T0, we want to predict T(t) for later time. As before, we transform the variable to reduce the differential corresponding to each solution curve? Then, by steps similar to previous examples, represent a heating object and how we? We make the following remarks??It is straightforward to verify that the initial temperature is T(0) = T0 (substitute t = 0 into the solution of Eqn. Since k > 0, this is an exponentially decaying function, whose magnitude shrinks with time. If T0 > E, the temperature approaches E from above, whereas if T0 < E, the temperature approaches E from below. Recognizing such general structure means that we can avoid repeating similar calculations from scratch in related examples. Next, we describe other examples that share this structure, and hence similar dynamic behaviour. Friction and terminal velocity A falling object accelerates under the force of gravity, but friction slows down this acceleration. We merely have to adjust the notation, by identifying the parameters in Example 12. Write down her velocity v(t) based Hence, without further calculation, we can conclude that the solution of on results of Example 12. Depending on the initial speed, the object either slows down (if v0 > g/k) or speed up (if v0 < g/k) as it approaches the terminal velocity. A second reaction results in decay of that substance at a rate proportional to its concentration. Let c(t) denote the time-dependent concentration of the substance, and assume that time is measured in units of hours. Diseases
The sport? minimize mental disorders or psychological distress be designation antiviral tablets order zovirax cream cheap, for those licensed psychologists antiviral drugs for flu cheap 5 gm zovirax cream visa, should cause of the expectations of strength hiv infection elisa purchase zovirax cream 5 gm on line, stability and men denote a competency in their training antiviral used to treat herpes 5 gm zovirax cream for sale. As a result, defned in most states, includes academic preparation, student-athletes often avoid disclosing a mental health training, supervision and experience within a specifc concern, especially if the perceived negative consequence domain (for example, child psychology, forensic psy includes being rejected by teammates or coaches due to chology). As sports medicine and athletic training have providers for collegiate student-athletes. This often requires that a licensed provider breadth of these models of course depend on the com have previous experience as perhaps a student-athlete mitment of the athletics administration, sports medicine, or coach, or a prior role within an athletics department academic services, compliance and coaching staffs to op (like an academic adviser), or have supervised experi timize psychological resources for their student-athletes. This position is typically held by a licensed experiential learning opportunities for the psychologist, counseling/clinical psychologist with graduate training which builds competency to provide care for the athlete. However, a few programs train students to be continues to focus on concepts such doctoral-level psychologists and provide graduate training/ experience in the domain of sport psychology (the Univer as performance excellence? and sity of North Texas and Indiana University, Bloomington, do so, for example, both in counseling psychology). Because collegiate ath letics continues to focus on concepts such as performance coaches? fnds college athletics excellence? and mental toughness,? the realm of motiva tional gurus? and mental coaches? fnds college athletics a prime target for their services, a prime target for their services, and they may very well and they may very well ignore, ignore, minimize or neglect the real issues of psychological health. Individuals not trained in mental health/psychology minimize or neglect the real issues often say they will refer any athlete with a personal issue, but if they are not trained in diagnostic interviewing, then of psychological health. Thus, the ath letics administrator must struggle with the challenge of pro for issues related to performance anxiety and viding effective mental health services for student-athletes, confdence issues); as well as providing a resource to teach coaches and stu-??Coordination of substance abuse/eating disor dent-athletes psychological skills to enhance sports perfor der services for student-athletes (often being in mance. It is import ics departments retain external consultants or counseling ant that schools explore all the options for a psychologi center staff psychologists who are given time to work cal services model for their student-athletes. These people typically Clearly, an immersed program with full-time or part provide the same services as their full-time counterparts, time licensed psychologists allows for better service, though with less time per week (about 10-30 hours as communication and delivery of services. Providing do not have the budget to develop a full-time position a psychologist as part of the support staff also helps to with benefts often choose this model. However, as sports medicine care has greatly en example, substance abuse counselor at counseling cen hanced prevention, intervention and rehabilitation of ter, mental skills consultant in physical education depart athletics injuries, an immersed and comprehensive sport ment) to be part of the team that the primary consultant psychology program can enhance the prevention, inter coordinates, supervises and directs. This model does University counseling centers offer unique services and not employ or retain an in-house? provider; rather, it benefts to student-athletes, including professionals who identifes a specifc provider within the community or are highly skilled in treating the mental health concerns counseling center that will take referrals for student-ath common to college students and who are of diverse back lete psychological issues. Counseling centers this model tends to be more of an intervention? also offer student-athletes a high level of confdentiality. Student-ath gist positions (either full-time or part-time) that are im letes will reap the beneft of this collaboration through mersed within the department, there will be greater edu improved emotional well-being. Vincent Sports Performance in Indianapolis and a counseling sport psychologist and coordinator of sport psychology services for the Purdue University athletics department. Carr also provides indi vidual counseling and consultation services, and he is a licensed psychologist in the state of Indiana. He is currently the consulting sport psychologist for the Indiana Pacers and has previously been the counseling sport psychologist for Indiana University, Bloomington, the Ohio State University and Washington State University. Jamie Davidson is a licensed psychologist with more than 20 years of clinical practice in higher education. He serves as the associate vice president for student wellness at the University of Nevada, Las Vegas, after having previously been the director of student counseling and psychological services there. The pressure associated with stu anxiety, panic disorder and phobic anxiety after an injury dent-athletes? daily routine can create intense emotional are more likely to be sports-related. The time, energy and effort put into develop disorder and obsessive-compulsive disorder are less like ing skills in a given sport can result in imbalances in other ly to be sports-related but are still common. Developmental and environmental infuenc Many athletes can experience anxiety that is either relat es shape emotional, motor and social aspects of the brain. Feeling overwhelmed? or stressed? are fre quent terms used at the time of presentation. Panic attacks are intense optimize health, improve athletics feelings of being overwhelmed with many physical symptoms such as racing heart, shortness of breath, performance and manage psychiatric shakiness and sweating that surface quickly. Phobias symptoms while operating within an may be related to an injury, recovery and return to play. Medical problems and sub the average age for onset of depression is approxi stance-induced conditions need to be ruled out before the mately 22, but it is decreasing. A??Anxiety disorders low frustration tolerance, isolation from teammates and??Mood disorders lack of enjoyment with deterioration in performance??Personality disorders is a part of the presentation with depression as well. The most common dent-athletes associated with performance are extraver emotions are anger, anxiety, sadness and guilt. Individuals with per common behaviors include aggression, arrests, insom sonality disorders experience interpersonal diffculties, nia, social isolation, substance use, relationship conficts, impulse control problems, misperception of comments or quitting and poor performance. Females more Some of the consequences related to substance use in likely will have the inattentive type. This condition the brain pathways involved can be reinforced from carries over into adulthood in about half of the cases. Alcohol and drug the severity of the symptoms can result in limitations use commonly co-occur with mental health problems. Males often present with effects of alcohol often present with performance prob denial, while females present tired and exhausted. The triad of impaired eating, amenorrhea and Ritalin)] is an increasing problem for student-athletes, es osteoporosis are the classic features in females. Student-athletes who begin using an opiate [for ing disorder progresses; however, disordered eating is example, hydrocodone (Vicodin), oxycodone (Percocet more common at presentation. As the condition worsens, and Oxycontin)] may continue to use it after their medical more impairment occurs. An individual who suf Eating disorders are more common in gymnastics and fers from an impulse control problem might exhibit epi swimming/diving, which are judged on aesthetics, and in sodes of aggression, fghting, and risky sexual behavior. Muscle dysmorphia is a sub of an emotional issue and occur more commonly in type that is characterized by an unhealthy preoccupation collision sports. Many warn leads to chronic functional impairment (or pain) in a stu ing signs emerge before suicide attempts that are often dent-athlete may manifest as a psychosomatic condition. More than two-thirds will have alcohol in their In addition to all of these, pain presents another challenge system at the time of the suicide attempt. There may be pressure to play the challenge for any athletics department is to be through the pain for fear of loss of a position or status. An aware of mental health issues and be trained to spot them athlete who is injured may experience a loss of identity. Untreated mental health problems result career bring challenges that have multiple associations to in undue suffering, diminished positive affect and bal physical health, mental health and emotional well-being ance in life. Most psychiatric disorders in student-athletes improve Over-training can look like clinical depression. He is a former high school and college football quarterback (Hastings College) and has spent a number of years working with col lege student-athletes while serving as consulting sport psychiatrist at the University of Nebraska. They tend to live healthier lives than studies suggest a strong genetic predisposition to develop non-athletes, and they gain skills in teamwork, discipline an eating disorder, and that these disorders aggregate in and decision-making that their non-athlete peers may not. Family and twin studies However, some aspects of the sports environment can have found heritability estimates of 76 percent for anorexia increase the risk of disordered eating (and eating disorders). Not all individ That means student-athletes and those who oversee athlet uals with a genetic predisposition develop the disorder, as ics must be vigilant to detect signs of trouble. All eating disorders involve disor fndings, the primary explanation for the development of dered eating, but not all disordered eating meets diagnostic eating disorders involved sociocultural factors. Once the disorder begins, sociocultural pressures usually plays in accounting for all physical activity, as well as to fuel assist in maintaining the disorder. Also, from a sociocultur normal bodily processes of health, growth and development. Eating disorders occur in all sports, but??Anxiety and/or depression??Claims of feeling fat? despite being thin not equally in all sports. As in society, eating disorders in??Excessive exercise sport occur more frequently in females than males. One??Excessive use of restroom area in which research fndings are more defnitive is for??Diffculty concentrating lean? sports for which a thin/lean body or low weight is??Preoccupation with weight and eating believed to provide a biomechanical advantage in perfor-??Avoidance of eating and eating situations mance or in the judging of performance. Women in these??Use of laxatives and diet pills sports are considered to be at the highest risk. Eating problems are often the way will increase sport performance individuals deal with such stressors. Just as society and culture to lose weight??Observed eating and exercise behaviors of team emphasize the thin ideal,? similar pressures exist in the mates and competitors sport environment regarding being thin/lean and its pur-??Revealing uniforms ported positive effect on sport performance. In society and sport, the relationship between body image and body dissat athletes are often expected to display a particular body size isfaction in female student-athletes is more conficted and or shape that becomes characteristic of a particular sport, confused than in the general population. Generic zovirax cream 5 gm. HIV-AIDS का कारण लक्षण और उपचार -1. Psychosocial predictors of treatment outcome antiviral medication for herpes buy 5 gm zovirax cream with amex, dropout antiviral remedies herpes order zovirax cream 5 gm on line, and change processes in a Pharmacological clinical trial for alcohol dependence acute hiv infection symptoms cdc buy zovirax cream 5 gm overnight delivery. Reliability and validity testing of the revised 12-item Short-Form Health Survey in older adults hiv transmission rates from infected female to male buy cheap zovirax cream. Simplified scoring and psychometrics of the revised 12-item Short-Form Health Survey. Inter-rater reliability of Global Assessment of Functioning in a clinical setting. Do acamprosate or naltrexone have an effect on daily drinking by reducing craving for alcohol? References 207 A Review of Screening, Assessment and Outcome Measures for Drug and Alcohol Settings Richter, P. Assessment and treatment of patients with coexisting mental illness and alcohol and other drug abuse. Journal of the American Academy of Child & Adolescent Psychiatry, 45(11), 1329-1337. Evidence for the Factorial Validity of the Dispositional Hope Scale Cross-Ethnic and Cross-Gender Measurement Equivalence. Factor Structure of Addiction Severity Index in an inpatient detoxification sample. Measuring patient symptom change on rural psychiatry units: Utility of the Symptom Checklist-90 Revised. The Strengths and Difficulties Self-Report Questionnaire as a screening instrument in Norwegian community samples. The Life Skills Profile: a measure assessing function and disability in schizophrenia. Consistency of self-administered and interview-based Addiction Severity Index composite scores. The prevalence of mental and physical health disorders among older methadone patients. References 208 A Review of Screening, Assessment and Outcome Measures for Drug and Alcohol Settings Rosenthal, T. Similarities and differences on five inventories among mood and anxiety disorder patients. Measuring outcomes of care for mental health problems: the case of depressive disorders. Evidence for limited validity of the revised global assessment of functioning scale. Screening for alcohol-related problems in an outpatient obstetric gynecologic clinic. Detecting risk drinking during pregnancy: a comparison of four screening questionnaires. Drug dependent patients in the methadone maintenance program: evaluation in primary care of psychosocial and organic severity. Quality of Life Research: An International Journal of Quality of Life Aspects of Treatment, Care & Rehabilitation, 11(1), 19 26. Beyond Ponce de Leon and life satisfaction: New directions in quest of successful aging. References 209 A Review of Screening, Assessment and Outcome Measures for Drug and Alcohol Settings Ryff, C. Psychometric properties of the Impact of Events Scale in traumatized Cambodian refugee youth. Utility of the Time-Line Follow-Back to assess substance use among homeless adults. A multivariate evaluation of the Michigan Alcoholism Screening Test and the Drug Abuse Screening Test in a female offender population. Prevalence and severity of mental health-related disability and relationship to diagnosis. Disability measurement in the anxiety disorders: comparison of three brief measures. Quality of Life Research: An International Journal of Quality of Life Aspects of Treatment, Care & Rehabilitation, 10(8), 711-721. References 210 A Review of Screening, Assessment and Outcome Measures for Drug and Alcohol Settings Schaffer, D. Predictors of positive psychosocial functioning of older adults in residential care facilities. The structure of post-traumatic stress disorder symptoms in three female trauma samples: A comparison of interview and self report measures. Ist der European Addiction Severity Index ein sinnvolles disgnoseinstrument bei alkhollabhangigkeit? Concurrent validity of the Global Assessment of Functioning Scale for clients with schizophrenia. References 211 A Review of Screening, Assessment and Outcome Measures for Drug and Alcohol Settings Scott, J. Concurrent and retrospective reports of alcohol consumption across 30, 90 and 366 days: Interactive voice response compared with the timeline follow back. Effects of Community Violence Exposure and Parental Mental Health on the Internalizing Problems of Urban Adolescents. The Michigan alcoholism screening test: the quest for a new diagnostic instrument. Treatment outcomes among adolescents with substance abuse problems: the relationship between comorbidities and post-treatment substance involvement. Pilot randomized controlled study of dexamphetamine substitution for amphetamine dependence. Screening for posttraumatic stress disorder in a general psychiatric outpatient setting. References 212 A Review of Screening, Assessment and Outcome Measures for Drug and Alcohol Settings Shields, A. The Michigan Alcoholism Screening Test and its shortened form: A meta-analytic inquiry into score reliability. Case Formulation in Psychotherapy: Revitalizing Its Usefulness as a Clinical Tool. Quality of life and its correlates in patients with dual diagnosis of bipolar affective disorder and substance dependence. Determination of the reliability and validity of the Marijuana Craving Questionnaire using imagery scripts. Survey of homelessness, alcohol consumption and related problems amongst Aboriginals in the Hedland area. References 213 A Review of Screening, Assessment and Outcome Measures for Drug and Alcohol Settings Smedje, H. Risperidone decreases craving and relapses in individuals with schizophrenia and cocaine dependence. The Canadian Journal of Psychiatry / La Revue canadienne de psychiatrie, 47(7), 671-675. A brief community linkage intervention for veterans with a persistent mental illness and a co-occurring substance abuse disorder. Cross cultural evaluation of two drinking assessment instruments: Alcohol Timeline Followback and Inventory of Drinking Situations. The reliability of the Alcohol Timeline Followback when administered by telephone and by computer. Caracterizacion del nivel de dependencia al alcohol entre habitantes de la Ciudad de Mexico. References 214 A Review of Screening, Assessment and Outcome Measures for Drug and Alcohol Settings Sourander, A. Effects of posttraumatic stress and acculturation on marital functioning in Bosnian refugee couples. Jia Yang (Poplar). Zovirax Cream.
Source: http://www.rxlist.com/script/main/art.asp?articlekey=96270 |